Name: TopPURE® HPV Cervical Sample Collection Kit (Bộ tự lấy mẫu HPV, HI-015) - ABT
Brand: Bộ thu và xử lý mẫu
SKU: HI-015

1. Information about Cervical Cancer and HPV cervical sample collection

Cervical cancer is a disease associated with abnormal proliferation of cells in the cervical epithelium (the organ between the uterus and the vagina), forming tumors in the uterus. Abnormal cervical cells exhibit characteristics such as multinucleation, increased pigmentation, and non-keratinization around the nucleus. The nucleus of abnormal cells is three times larger than that of normal cells. Changes in nuclear shape and cellular substance form the basis for cytological methods in UTCTC early screening.

Based on cell type, cervical cancer is divided into two main types: squamous cell carcinoma (SCC) and adenocarcinoma (AC). SCC occurs in the epithelial cells at the outer location of the cervix and is more common, while AC occurs in the endocrine glands of the cervix.

The main cause of cervical cancer is the Human papillomavirus (HPV) is a virus that causes papillomas (warts) in humans and animals. HPV (Human papillomavirus) spread through the genital tract through unsafe ways. According to the World Health Organization (WHO), cervical cancer is the fourth most common disease in women worldwide. According to Globocan statistics, 185 out of 204 countries in the world report on the situation of cervical cancer. Of which, Vietnam ranks 91/185 in terms of new incidence rate and 50/185 in terms of mortality rate in the world.

The TopPURE® HPV Cervical Sample Collection Kit serves as a product designed for the collection, preservation, and transportation of vaginal swab specimens, specifically intended for real-time PCR (qPCR) tests for the detection of Human papillomavirus (HPV). The kit components include:

Cervical sampler: Swab material: Medical-grade foam + ABS plastic. Swab length: 133mm.
Sample transport medium: 3 mL of medium contained in a 7 mL centrifuge tube. The solution is clear, colorless, with a pH of 6.8±0.5.
Zip-lock bag: Used for containing tubes for the transportation of clinical specimens.

2. Manual intructions

3. Note

Gloves and masks should be worn during the procedure.
Avoid use during menstruation, pregnancy and lactation.
It is not recommended for women with genital tract injuries or those who have recently undergone cervical surgery. Cervical inflammation should ideally be treated prior to sample collection, and sampling should occur post-recovery.
Abstaining from sexual intercourse within 24 hours preceding sample collection is advisable.
Vaginal douching or intravaginal medication should not be performed within 3 days prior to sample collection.
Do not use if the packaging is damaged, the sampling tip is in contact with the tube or the sampling tip is separated from the tube, or the product has expired.
In case of persistent bleeding or pain during the sampling procedure, immediate cessation is advised, and medical attention should be sought promptly.
Waste must be treated according to legal documents and regulations on national environmental protection.

For Real-time Kit: TopSENSI ® HPV qPCR KIT (SQH-103)