ABT® HPV qPCR KIT (RUO) (SQH-004)

HPV introduction

Human Papillomavirus (HPV) is a common sexually transmitted DNA virus. It is recognized as the etiological agent of a spectrum of diseases in both males and females, including precancerous lesions that may progress to malignancy and the formation of genital warts.

Although the majority of HPV infections are asymptomatic and resolve spontaneously, persistent infection can lead to pathology. In women, chronic infection with specific high-risk genotypes—most notably types 16 and 18—can induce precancerous cervical lesions that, if untreated, may advance to invasive cervical carcinoma. HPV is also implicated in oropharyngeal and anogenital cancers as well as other disease entities in both sexes.

More than 100 HPV genotypes have been identified, each designated by a numerical identifier. Certain low-risk genotypes cause anogenital warts but lack oncogenic potential. However, nearly all cases of cervical cancer (approximately 99 percent) are attributable to genital HPV infection. Fourteen high-risk genotypes are classified as carcinogenic—types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68—with types 16 and 18 together accounting for roughly 70 percent of global cervical cancer cases.

ABT® HPV qPCR Kit is a test kit used to detect the presence of HPV-DNA present in Samples were extracted from cervical smear/biopsy samples using Real-time PCRtechnique. In particular, the kit uses the endogenous RP internal control to help effectively control the sample collection, extraction and PCR process.

ABT® HPV qPCR Kit Advantages

• Simple process easy manipulation
• PCR execution time is quick, only about 2 hours
• High specificity and sensitivity
• Taqman probe technology

ABT® HPV qPCR Kit

SPECIFICATIONS

 Recommended extraction kit

Read more: Instructional Video for Qualitative Real-time PCR Kit