{"id":12218,"date":"2025-02-22T09:20:12","date_gmt":"2025-02-22T01:50:12","guid":{"rendered":"https:\/\/abtvn.com\/?post_type=product&#038;p=12218"},"modified":"2025-10-21T11:30:16","modified_gmt":"2025-10-21T04:00:16","slug":"abt-cervical-cytology-manual-kit-dd-102","status":"publish","type":"product","link":"https:\/\/abtvn.com\/en\/product\/abt-cervical-cytology-manual-kit-dd-102\/","title":{"rendered":"ABT\u00ae CERVICAL CYTOLOGY MANUAL KIT (DD-102)"},"content":{"rendered":"<h2><strong>Information about Cervical Cancer<\/strong><strong> and <\/strong><strong>ABT \u00ae Cervical Cytology Manual Kit<\/strong><\/h2>\n<p>&nbsp;<\/p>\n<p><em><strong>Cervical cancer<\/strong><\/em> is a disease associated with the abnormal proliferation of epithelial cells in the cervix (the organ connecting the uterus and the vagina), forming tumors in the uterus. Abnormal cervical cells exhibit the following characteristics: multinucleation, hyperchromasia, and cytoplasmic vacuolization around the nucleus. The nuclei of abnormal cells are three times larger than those of normal cells. Changes in nuclear and cytoplasmic morphology form the basis for cytological methods in early screening for cervical cancer. Based on the cell type, cervical cancer is classified into two main types: squamous cell carcinoma (SCC) and adenocarcinoma (AC). SCC occurs in the epithelial cells at the outer cervix and is more common, while AC occurs in the glandular cells of the cervix.<\/p>\n<p>The main cause of cervical cancer is the <a href=\"https:\/\/www.who.int\/teams\/health-product-policy-and-standards\/standards-and-specifications\/vaccine-standardization\/human-papillomavirus\" target=\"_blank\" rel=\"noopener\"><em>Human papillomavirus<\/em><\/a> (HPV), a virus that causes papillomas in humans and animals. HPV spreads through genital contact via unsafe sexual activities. According to the World Health Organization (WHO), cervical cancer is the fourth most common cancer among women worldwide. In 2020, there were approximately 604,000 new cases and 342,000 deaths from cervical cancer. About 90% of new cases and deaths occurred in low- and middle-income countries. According to Globocan statistics, 185 out of 204 countries worldwide report on the situation of cervical cancer. Vietnam ranks 91st out of 185 in terms of new incidence rate and 50th out of 185 in terms of mortality rate globally. This shows a significant increase compared to 2018, where the new incidence rate was 99th out of 185, and the mortality rate was 56th out of 185.<\/p>\n<p class=\"translation-block\"><strong>ABT\u00ae Cervical Cytology Manual Kit<\/strong> is a tool for collecting, processing, and spreading gynecological cells using centrifugation combined with natural sedimentation. Cervical smear samples are collected at the cervix, processed to remove mucus and blood from the sample matrix, and stabilized in an alcohol-based buffer solution for up to one month at a temperature range of 15\u201325\u00b0C, serving cytological testing purposes (liquid-based Pap test) for cervical cancer screening. Additionally, smear samples collected and preserved using the kit can be processed for HPV-DNA testing.<\/p>\n<p>The <strong>ABT \u00ae Cervical Cytology Manual Kit <\/strong>(DD-102) including:<\/p>\n<p><strong>- Sample collection swab:<\/strong><\/p>\n<ul>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Material: PE + PP<\/span><\/li>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Sample collection head diameter: 19.5 \u00b1 2 mm<\/span><\/li>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Total length: 202\u00b110 mm<\/span><\/li>\n<\/ul>\n<p>&#8211; <strong>ABT\u00ae Cell Preservative Solution:<\/strong><\/p>\n<ul>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">A homogeneous, transparent, colorless liquid, free from impurities and sediment. It has the characteristic odor of the product without any unusual smells. pH 5.5 \u00b1 0.2.<\/span><\/li>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Sample storage duration: Within one month from the collection date.<\/span><\/li>\n<\/ul>\n<p><strong>- Cell sedimentation chamber<\/strong><\/p>\n<ul>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Material: PE + PP<\/span><\/li>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Dimensions: 35 mm \u00d7 20 mm \u00d7 15 mm (Height \u00d7 Body Diameter \u00d7 Base Diameter)<\/span><\/li>\n<\/ul>\n<p><strong>- Microscope slide:<\/strong><\/p>\n<ul>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Material: Glass<\/span><\/li>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Dimensions: 75 mm \u00d7 25 mm \u00d7 1 mm (Length \u00d7 Width \u00d7 Thickness)<\/span><\/li>\n<\/ul>\n<p><strong>&#8211; <span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">ABT \u00ae Density Solution<\/span>:<\/strong><\/p>\n<ul>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">A homogeneous, transparent, colorless liquid with slight viscosity, free from impurities and sediment. It has the characteristic odor of the product without any unusual smells.<\/span><\/li>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Processing capability: Processes and removes mucus, blood, and inflammatory cells in gynecological smear samples (GYN) and collects target epithelial cells.<\/span><\/li>\n<\/ul>\n<p><strong>&#8211; <span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">ABT \u00ae Dilute Solution<\/span>:<\/strong><\/p>\n<ul>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">A homogeneous, transparent, colorless liquid with slight viscosity, free from impurities and sediment. It has the characteristic odor of the product without any unusual smells.<\/span><\/li>\n<li><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">Processing capability: Separates and evenly distributes cells on the slide during smear preparation.<\/span><\/li>\n<\/ul>\n<h2><strong>Manual instruction <\/strong><strong>ABT \u00ae <\/strong><strong>Cervical Cytology Manual Kit<\/strong><\/h2>\n<p><em><strong>1. Sample preparation:<\/strong><\/em><\/p>\n<p>Cervical smear samples will be collected according to the Ministry of Health's procedure (Appendix 1, Decision 3877\/QD-BYT 2019):<\/p>\n<ul>\n<li><strong>Step 1: <\/strong>Insert a speculum into the vagina and adjust its position to ensure a clear view of the cervix.<\/li>\n<li><strong>Step 2: <\/strong>Insert the sampling brush into the cervix, press gently, and rotate the brush clockwise 5 times (Figure 1).<\/li>\n<li><strong>Step 3: <\/strong>Remove the sampling brush from the vagina and place it into the ABT\u00ae Cell Preservative Solution vial, gently rotating it 5 to 10 times. The head of the sampling brush is retained by detaching it from the handle, and the handle is disposed of properly.<\/li>\n<li><strong>Step 4:<\/strong> Close the vial and record the patient's information on the label with a pencil.<\/li>\n<\/ul>\n<p class=\"translation-block\">Store and transport the sample at room temperature (15-25\u2103) for up to 1 month for cytological examination (liquid-based Pap test) in cervical cancer screening. Additionally, samples collected and preserved using the kit can be processed for HPV-DNA testing.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-9497 size-medium lazyload\" data-src=\"https:\/\/abtvn.com\/wp-content\/uploads\/2023\/12\/screenshot_1703494485-e1732683736703-300x161.png\" alt=\"cervical cytology\" width=\"300\" height=\"161\" data-srcset=\"https:\/\/abtvn.com\/wp-content\/uploads\/2023\/12\/screenshot_1703494485-e1732683736703-300x161.png 300w, https:\/\/abtvn.com\/wp-content\/uploads\/2023\/12\/screenshot_1703494485-e1732683736703-18x10.png 18w, https:\/\/abtvn.com\/wp-content\/uploads\/2023\/12\/screenshot_1703494485-e1732683736703.png 537w\" data-sizes=\"(max-width: 300px) 100vw, 300px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/161;\" \/><\/p>\n<p style=\"text-align: center;\"><em><strong>Figure 1<\/strong><\/em> Position for placing the cervical smear sampling brush.<\/p>\n<p><em><strong>2.<\/strong><\/em> <strong>Processing and smearing slides<\/strong><\/p>\n<p>- Record patient information on the frosted edge of the electrostatic glass slide using a pencil and on the cell sedimentation chamber filter cup and plastic pipette using a marker.<\/p>\n<p>- Proceed with sample processing and smear preparation using a Falcon centrifuge according to the following steps:<\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li><strong>Step 1:<\/strong>Vortex the sample thoroughly for 30 seconds and transfer 7 mL of the sample solution into a 15 mL Falcon tube.<\/li>\n<li><strong>Step 2:<\/strong> Use a plastic pipette to aspirate 3 mL of ABT\u00ae Density Solution and carefully dispense it to the bottom of the tube, allowing it to gently settle so that the sample solution and ABT\u00ae Density Solution form two distinct layers.<\/li>\n<li><strong>Step 3:<\/strong> Centrifuge at 4000 rpm for 10 minutes. Use a plastic pipette to remove approximately 7 mL of the supernatant, avoiding aspiration of the precipitate in the tube.<\/li>\n<li><strong style=\"font-size: 16px;\">Step 4:<\/strong><span style=\"font-size: 16px;\"> Centrifuge again at 4000 rpm for 5 minutes to collect the cell pellet. Use a plastic pipette to remove the remaining supernatant and retrieve the precipitate.<\/span><\/li>\n<li><strong>Step 5:<\/strong> Add approximately 1\u20135 mL of ABT\u00ae Dilute Solution (maintaining a sample\/ABT\u00ae Dilute Solution ratio of 1:20) to dilute the sample.<\/li>\n<li><strong>Step 6:<\/strong> Assemble the glass slide and sedimentation chamber on the plastic tray. Pipette 500 \u00b5L of the diluted sample directly onto the sedimentation chamber and let it sit for 5 minutes.<\/li>\n<li><strong>Step 7:<\/strong> Remove the supernatant and retrieve the glass slide containing the cells.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>- After smearing, fix the glass slide in 96% ethanol for 15 minutes and stain with PAP according to the procedure of the <strong>ABT \u00ae Papanicolaou Staining Kit (DD-083; DD-084)<\/strong>.<\/p>\n<p>- Observe and analyze the results under a microscope.<\/p>\n<p><strong>Note:\u00a0 <\/strong><\/p>\n<p>- Always wear gloves and a mask during the procedure.<\/p>\n<p>\u2013 Shake the ABT\u00ae Cell Preservative Solution well before opening the cap for use.<\/p>\n<p>\u2013 The appropriate sample collection time is within 2 days before or after menstruation.<\/p>\n<p>\u2013 Contraindicated in pregnant women.<\/p>\n<p>\u2013 Waste must be disposed of according to national environmental protection laws and regulations.<\/p>\n<p><strong style=\"font-size: 16px;\">3. Recommendations:<\/strong><\/p>\n<p>Compatible with centrifuge models designed for 15 mL Falcon tubes.<\/p>\n<p>Read more: T<a href=\"https:\/\/abtvn.com\/en\/product\/toppure-hpv-pap-smear-kit-hi-017\/\">opPURE\u00ae HPV Pap Smear Kit (HI-017)<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p><strong>Intended uses<\/strong>: <strong>ABT \u00ae<\/strong> <strong>Cervical Cytology Manual Kit <\/strong>is a tool for collecting, processing, and spreading gynecological cells using centrifugation combined with natural sedimentation. Cervical smear samples are collected at the cervix, processed to remove mucus and blood from the sample matrix, and stabilized in an alcohol-based buffer solution for up to one month at a temperature range of 15\u201325\u00b0C.<sup>o<\/sup>C.<\/p>\n<p><strong>Storage: <\/strong>Room temperature 15-25<sup>o<\/sup>C, avoiding direct light exposure.<\/p>\n<p><strong>Expiration Date<\/strong>: 12 months from manufacture 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Team","author_link":"https:\/\/abtvn.com\/en\/author\/"},"uagb_comment_info":0,"uagb_excerpt":"M\u1ee5c \u0111\u00edch: ABT \u00ae Cervical Cytology Manual Kit l\u00e0 m\u1ed9t b\u1ed9 d\u1ee5ng c\u1ee5 thu nh\u1eadn, x\u1eed l\u00fd v\u00e0 ph\u1ebft t\u1ebf b\u00e0o ph\u1ee5 khoa b\u1eb1ng k\u1ef9 thu\u1eadt ly t\u00e2m k\u1ebft h\u1ee3p v\u1edbi l\u1eafng t\u1ef1 nhi\u00ean. M\u1eabu d\u1ecbch ph\u1ebft \u0111\u01b0\u1ee3c thu nh\u1eadn t\u1ea1i v\u1ecb tr\u00ed c\u1ed5 t\u1eed cung s\u1ebd \u0111\u01b0\u1ee3c x\u1eed l\u00fd lo\u1ea1i b\u1ecf nh\u1ea7y v\u00e0 m\u00e1u&hellip;","_links":{"self":[{"href":"https:\/\/abtvn.com\/en\/wp-json\/wp\/v2\/product\/12218","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/abtvn.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/abtvn.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/abtvn.com\/en\/wp-json\/wp\/v2\/comments?post=12218"}],"version-history":[{"count":5,"href":"https:\/\/abtvn.com\/en\/wp-json\/wp\/v2\/product\/12218\/revisions"}],"predecessor-version":[{"id":13025,"href":"https:\/\/abtvn.com\/en\/wp-json\/wp\/v2\/product\/12218\/revisions\/13025"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/abtvn.com\/en\/wp-json\/wp\/v2\/media\/12219"}],"wp:attachment":[{"href":"https:\/\/abtvn.com\/en\/wp-json\/wp\/v2\/media?parent=12218"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/abtvn.com\/en\/wp-json\/wp\/v2\/product_brand?post=12218"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/abtvn.com\/en\/wp-json\/wp\/v2\/product_cat?post=12218"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/abtvn.com\/en\/wp-json\/wp\/v2\/product_tag?post=12218"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}