{"id":6960,"date":"2022-08-07T04:37:57","date_gmt":"2022-08-06T21:07:57","guid":{"rendered":"https:\/\/abtvn.com\/?p=6960"},"modified":"2023-04-06T14:42:44","modified_gmt":"2023-04-06T07:12:44","slug":"ngay-viem-gan-the-gioi-28-7-bao-ve-la-gan-bao-ve-co-the","status":"publish","type":"post","link":"https:\/\/abtvn.com\/en\/ngay-viem-gan-the-gioi-28-7-bao-ve-la-gan-bao-ve-co-the\/","title":{"rendered":"Ng\u00e0y vi\u00eam gan th\u1ebf gi\u1edbi 28-7: B\u1ea3o v\u1ec7 l\u00e1 gan \u2013 B\u1ea3o v\u1ec7 c\u01a1 th\u1ec3<\/strong>"},"content":{"rendered":"

Nh\u00e2n ng\u00e0y th\u1ebf gi\u1edbi c\u00f9ng nhau ph\u00f2ng ch\u1ed1ng b\u1ec7nh vi\u00eam gan. Tr\u01b0\u1eddng Y khoa Johns Hopkins t\u1ea1i Vi\u1ec7t Nam, Trung t\u00e2m nghi\u00ean c\u1ee9u b\u1ec7nh truy\u1ec1n nhi\u1ec5m c\u1ee7a \u0110\u1ea1i h\u1ecdc Qu\u1ed1c t\u1ebf v\u00e0 Khoa Y-\u0110HQG TP HCM \u0111\u00e3 h\u1ee3p t\u00e1c t\u1ed5 ch\u1ee9c H\u1ed8I NGH\u1eca VI\u00caM GAN VIRUS B-C v\u00e0 UNG TH\u01af GAN T\u1ea0I VI\u1ec6T NAM – VICLD-2022 – Th\u1ef1c tr\u1ea1ng hi\u1ec7n t\u1ea1i v\u00e0 h\u01b0\u1edbng \u0111i t\u01b0\u01a1ng lai.<\/p>\n\n\n\n

ABT \u0111\u00e3 c\u00f3 m\u1eb7t t\u1ea1i h\u1ed9i ngh\u1ecb c\u00f9ng nh\u1eefng nh\u00e0 nghi\u00ean c\u1ee9u v\u00e0 c\u00e1c b\u00e1c s\u0129 l\u00e2m s\u00e0ng h\u00e0ng \u0111\u1ea7u trong c\u00e1c l\u0129nh v\u1ef1c vi\u00eam gan virus v\u00e0 ung th\u01b0 gan \u0111\u1ec1 ra nh\u1eefng ch\u01b0\u01a1ng tr\u00ecnh \u0111i\u1ec1u tr\u1ecb ung th\u01b0 gan do virus. M\u1ed9t trong nh\u1eefng b\u1ec7nh ti\u00eau bi\u1ec3u \u1edf Vi\u1ec7t Nam v\u00e0 n\u01b0\u1edbc ngo\u00e0i.<\/p>\n\n\n\n

\"Ng\u00e0y<\/figure>\n\n\n\n

Ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan (HCC) l\u00e0 m\u1ed9t trong nh\u1eefng b\u1ec7nh ung th\u01b0 t\u00e1i ph\u00e1t v\u00e0 g\u00e2y t\u1eed vong nhi\u1ec1u nh\u1ea5t tr\u00ean to\u00e0n th\u1ebf gi\u1edbi, c\u00f3 li\u00ean quan ch\u1eb7t ch\u1ebd v\u1edbi nhi\u1ec5m tr\u00f9ng m\u00e3n t\u00ednh do vi r\u00fat vi\u00eam gan B (HBV), vi r\u00fat vi\u00eam gan C (HCV). B\u1ec7nh nh\u00e2n khi nhi\u1ec5m b\u1ec7nh nhi\u1ec1u tr\u01b0\u1eddng h\u1ee3p s\u1ebd kh\u00f4ng c\u00f3 tri\u1ec7u ch\u1ee9ng bi\u1ec3u hi\u1ec7n s\u1edbm, \u0111i\u1ec1u n\u00e0y g\u00e2y kh\u00f3 kh\u0103n trong ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb.<\/p>\n\n\n\n

Theo b\u00e1c s\u0129 Huy \u2013 Ph\u00f3 gi\u00e1m \u0111\u1ed1c trung t\u00e2m Gan, Tr\u01b0\u1edfng khoa U gan b\u00eanh vi\u1ec7n Ch\u1ee3 R\u1eaby chia s\u1ebb. Giai \u0111o\u1ea1n 2010-2021 t\u1ea1i Vi\u1ec7t Nam c\u00f3 42.495 ca nhi\u1ec5m Ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan m\u1edbi. T\u1ec9 l\u1ec7 m\u1eafc ung th\u01b0 gan \u1edf nam cao h\u01a1n 4.57 l\u1ea7n so v\u1edbi n\u1eef.<\/p>\n\n\n\n

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 H\u00ecnh 1: T\u00ecnh h\u00ecnh ph\u00e2n b\u1ed1 c\u00e1c ca nhi\u1ec5m ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan theo gi\u1edbi t\u00ednh.<\/em>
(Ngu\u1ed3n: B\u00e1o c\u00e1o t\u1eeb B\u00e1c s\u0129 Huy, Ph\u00f2ng Ung th\u01b0 Gan t\u1ea1i h\u1ed9i ngh\u1ecb)<\/em><\/figcaption><\/figure>\n\n\n\n

M\u1ee5c ti\u00eau chi\u1ebfn l\u01b0\u1ee3c qu\u1ea3n l\u00fd \u0111\u1ec3 gi\u1ea3m thi\u1ec3u Ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan bao g\u1ed3m:<\/p>\n\n\n\n

+ Gi\u1ea3m t\u1ec9 l\u1ec7 m\u1eafc Ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan<\/p>\n\n\n\n

+ T\u0103ng t\u1ec9 l\u1ec7 ph\u00e1t hi\u1ec7n s\u1edbm Ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan<\/p>\n\n\n\n

+ N\u00e2ng cao ch\u1ea5t l\u01b0\u1ee3ng ch\u1ea9n \u0111o\u00e1n Ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan<\/p>\n\n\n\n

+ N\u00e2ng cao kh\u1ea3 n\u0103ng \u0111i\u1ec1u tr\u1ecb: T\u0103ng c\u01a1 h\u1ed9i \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb \u0111\u00fang b\u1ec7nh, gi\u1ea3m hi\u1ec7n tr\u1ea1ng qu\u1ea3 t\u1ea3i b\u1ec7nh vi\u1ec7n tuy\u1ebfn trung \u01b0\u01a1ng gi\u00fap gi\u1ea3m thi\u1ec3u chi ph\u00ed cho b\u1ec7nh vi\u1ec7n. T\u1eadp trung v\u00e0o nh\u00f3m b\u1ec7nh c\u00f3 kh\u1ea3 n\u0103ng \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3 ho\u1eb7c nh\u00f3m b\u1ec7nh nh\u00e2n trong giai \u0111o\u1ea1n n\u1eb7ng.<\/p>\n\n\n\n

+ T\u0103ng c\u01b0\u1eddng h\u1ec7 th\u1ed1ng qu\u1ea3n l\u00fd, theo d\u00f5i b\u1ec7nh nh\u00e2n sau \u0111i\u1ec1u tr\u1ecb: gi\u00fap cung c\u1ea5p d\u1eef li\u1ec7u \u0111\u1ea7y \u0111\u1ee7 v\u00e0 ch\u00ednh x\u00e1c cho vi\u1ec7c ho\u1ea1ch \u0111\u1ecbnh ch\u00ednh s\u00e1ch.<\/p>\n\n\n\n

Th\u00e1ch th\u1ee9c trong chi\u1ebfn l\u01b0\u1ee3c gi\u1ea3m vi\u00eam gan, ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan hi\u1ec7n nay<\/strong><\/h2>\n\n\n\n

Hi\u1ec7n nay do t\u1ec9 l\u1ec7 vaccine HBV c\u00f2n \u00edt, h\u1ec7 th\u1ed1ng gi\u00e1m s\u00e1t c\u0169ng nh\u01b0 thu th\u1eadp d\u1eef li\u1ec7u v\u1ec1 con \u0111\u01b0\u1eddng lan truy\u1ec1n vi\u00eam gan c\u00f2n h\u1ea1n ch\u1ebf. \u0110i\u1ec1u n\u00e0y g\u00e2y th\u00e1ch th\u1ee9c l\u1edbn trong chi\u1ebfn l\u01b0\u1ee3c gi\u1ea3m thi\u1ec3u Ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan t\u1ea1i Vi\u1ec7t Nam.<\/p>\n\n\n\n

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H\u00ecnh 2: T\u00ecnh h\u00ecnh ph\u00e2n b\u1ed1 c\u00e1c ca nhi\u1ec5m ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan theo \u0111\u1ed9 tu\u1ed5i (Ngu\u1ed3n: B\u00e1o c\u00e1o t\u1eeb B\u00e1c s\u0129 Huy, Ph\u00f2ng Ung th\u01b0 Gan t\u1ea1i h\u1ed9i ngh\u1ecb)<\/em><\/em><\/figcaption><\/figure>\n\n\n\n

S\u1ed1 l\u01b0\u1ee3ng b\u1ec7nh nh\u00e2n c\u00f3 xu h\u01b0\u1edbng gi\u1ea3m t\u1eeb n\u0103m 2019. Nguy\u00ean nh\u00e2n \u0111\u01b0\u1ee3c cho l\u00e0 vi\u1ec7c duy tr\u00ec \u0111i\u1ec1u tr\u1ecb t\u1ea1i c\u00e1c c\u01a1 s\u1edf y t\u1ebf \u0111\u1ecba ph\u01b0\u01a1ng v\u00e0 \u1ea3nh h\u01b0\u1edfng do d\u1ecbch Covid-19. S\u1ed1 l\u01b0\u1ee3ng b\u1ec7nh nh\u00e2n 30 tu\u1ed5i kh\u00f4ng c\u00f3 nhi\u1ec1u do \u0111\u00e3 \u0111\u01b0\u1ee3c ti\u00eam vaccin ph\u00f2ng HBV. Tuy nhi\u00ean, s\u1ed1 b\u1ec7nh nh\u00e2n 30-40 tu\u1ed5i c\u00f3 xu h\u01b0\u1edbng t\u0103ng nhanh.<\/p>\n\n\n\n

<\/p>\n\n\n\n

\"ca
H\u00ecnh 3: 21521 (50.64%) ca nhi\u1ec5m ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n \u1edf giai \u0111o\u1ea1n mu\u1ed9n<\/em>
 (Ngu\u1ed3n: B\u00e1o c\u00e1o t\u1eeb B\u00e1c s\u0129 Huy, Ph\u00f2ng Ung th\u01b0 Gan t\u1ea1i h\u1ed9i ngh\u1ecb)<\/em><\/figcaption><\/figure>\n\n\n\n

C\u0169ng theo B\u00e1c S\u0129 Huy, 50.64% tr\u01b0\u1eddng h\u1ee3p ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan m\u1edbi ph\u00e1t hi\u1ec7n \u0111\u00e3 \u1edf giai \u0111o\u1ea1n mu\u1ed9n. L\u00ed do c\u00f3 th\u1ec3 v\u00ec:<\/p>\n\n\n\n

+ HCC th\u01b0\u1eddng ti\u1ebfn tri\u1ec3n b\u1ec7nh m\u1ed9t c\u00e1ch \u00e2m th\u1ea7m. B\u1ec7nh nh\u00e2n kh\u00f4ng bi\u1ec3u hi\u1ec7n tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng c\u1ee5 th\u1ec3.<\/p>\n\n\n\n

+ Gi\u00e1m s\u00e1t c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng c\u00f3 nguy c\u01a1 r\u1ee7i ro c\u00f2n nhi\u1ec1u h\u1ea1n ch\u1ebf.<\/p>\n\n\n\n

+ Nh\u1eadn th\u1ee9c c\u1ee7a ng\u01b0\u1eddi d\u00e2n v\u1ec1 vi\u1ec7c kh\u00e1m s\u1ee9c kh\u1ecfe \u0111\u1ecbnh k\u00ec l\u00e0 ch\u01b0a cao.<\/p>\n\n\n\n

+Hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb vi\u00eam gan do virus c\u00f2n hi\u1ec7u h\u1ea1n ch\u1ebf.<\/p>\n\n\n\n

B\u00e1c s\u0129 c\u0169ng \u0111\u1ec1 ra c\u00e1c gi\u1ea3i ph\u00e1p t\u0103ng c\u01b0\u1eddng ch\u1ea5t l\u01b0\u1ee3ng ch\u1ea9n \u0111o\u00e1n vi\u00eam gan. \u0110\u01b0a ra ti\u1ec1m n\u0103ng cho tr\u1ecb li\u1ec7u v\u00e0 c\u1ee7ng c\u1ed1 h\u1ec7 th\u1ed1ng qu\u1ea3n l\u00fd theo d\u00f5i b\u1ec7nh nh\u00e2n sau \u0111i\u1ec1u tr\u1ecb.<\/p>\n\n\n\n

Ph\u01b0\u01a1ng ph\u00e1p m\u1edbi ti\u1ebfp c\u1eadn s\u00e0ng l\u1ecdc s\u1edbm b\u1ec7nh vi\u00eam gan<\/strong><\/p>\n\n\n\n

Trong phi\u00ean h\u1ed9i ngh\u1ecb \u0111\u00e3 \u0111\u01b0a ra th\u1ef1c tr\u1ea1ng v\u00e0 nhi\u1ec1u h\u01b0\u1edbng ti\u1ebfp c\u1eadn ch\u1ea9n \u0111o\u00e1n b\u1ec7nh vi\u00eam gan. M\u1ed9t trong s\u1ed1 \u0111\u00f3 l\u00e0 nghi\u00ean c\u1ee9u ph\u01b0\u01a1ng ph\u00e1p m\u1edbi trong ch\u1ea9n \u0111o\u00e1n ung th\u01b0 gan b\u1eb1ng miRNA  nh\u01b0 m\u1ed9t biomarker \u0111\u1ed9t ph\u00e1 gi\u00fap s\u00e0ng l\u1ecdc, k\u1ebft h\u1ee3p v\u1edbi ph\u01b0\u01a1ng ph\u00e1p l\u00e2m s\u00e0ng hi\u1ec7n \u0111\u1ea1i ch\u1ea9n \u0111o\u00e1n b\u1ec7nh nh\u00e2n nhi\u1ec5m vi\u00eam gan.<\/p>\n\n\n\n

Theo nghi\u00ean c\u1ee9u c\u1ee7a Ti\u1ebfn s\u0129 Nguy\u1ec5n B\u1ea3o Qu\u1ed1c v\u00e0 c\u1ed9ng s\u1ef1, nh\u00f3m \u0111\u00e3 tr\u00ecnh b\u00e0y c\u00e1ch ph\u00e1t hi\u1ec7n HBV tr\u1ef1c ti\u1ebfp t\u1eeb m\u1eabu m\u00e1u b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p LAMP (Khu\u1ebfch \u0111\u1ea1i \u0111\u1eb3ng nhi\u1ec7t) v\u00e0 bi\u1ec3u hi\u1ec7n profile c\u1ee7a has-miR122.<\/p>\n\n\n\n

\"h\u1ed9i
H\u00ecnh 4: Phi\u00ean th\u1ea3o lu\u1eadn trao \u0111\u1ed5i gi\u1ea3i \u0111\u00e1p th\u1eafc m\u1eafc gi\u1eefa h\u1ed9i ngh\u1ecb (Ngu\u1ed3n: Fanpage Vietnam Association for Research on Liver Diseases<\/a>)<\/em><\/figcaption><\/figure>\n\n\n\n

Tr\u1ea3 l\u1eddi c\u00e2u h\u1ecfi t\u1eeb \u0111\u1ea1i di\u1ec7n ABT:<\/strong> Xin ch\u00e0o qu\u00fd anh\/ch\u1ecb trong h\u1ed9i tr\u01b0\u1eddng, C\u00f4ng ty GI\u1ea2I PH\u00c1P Y SINH ABT l\u00e0 doanh nghi\u1ec7p s\u1ea3n xu\u1ea5t kit t\u00e1ch chi\u1ebft, kit ch\u1ea9n \u0111o\u00e1n. \u0110\u1eb7c bi\u1ec7t ph\u00e1t tri\u1ec3n b\u1ed9 kit \u0111\u1ecbnh t\u00ednh\/\u0111\u1ecbnh l\u01b0\u1ee3ng HBV, HCV. ABT mu\u1ed1n h\u1ecfi ph\u01b0\u01a1ng ph\u00e1p m\u1edbi c\u1ee7a nh\u00f3m nghi\u00ean c\u1ee9u c\u00f3 ti\u1ec1m n\u0103ng th\u1ebf n\u00e0o \u0111\u1ec3 ph\u00e1t tri\u1ec3n th\u00e0nh m\u1ed9t b\u1ed9 sinh ph\u1ea9m ch\u1ea9n \u0111\u00f3an trong t\u01b0\u01a1ng lai? So s\u00e1nh ph\u01b0\u01a1ng ph\u00e1p s\u00e0ng l\u1ecdc hi\u1ec7n t\u1ea1i b\u1eb1ng real-time PCR th\u00ec n\u00f3 c\u00f3 \u01b0u \u0111i\u1ec3m kh\u00e1c bi\u1ec7t th\u1ebf n\u00e0o?<\/p>\n\n\n\n