{"id":13804,"date":"2025-10-28T16:28:09","date_gmt":"2025-10-28T08:58:09","guid":{"rendered":"https:\/\/abtvn.com\/?p=13804"},"modified":"2025-12-29T12:15:33","modified_gmt":"2025-12-29T04:45:33","slug":"kiem-soat-tap-nhiem-voi-mang-loc-hepa","status":"publish","type":"post","link":"https:\/\/abtvn.com\/en\/kiem-soat-tap-nhiem-voi-mang-loc-hepa\/","title":{"rendered":"Ki\u1ec3m so\u00e1t t\u1ea1p nhi\u1ec5m trong sinh h\u1ecdc ph\u00e2n t\u1eed v\u1edbi m\u00e0ng l\u1ecdc HEPA<\/strong>"},"content":{"rendered":"

Trong sinh h\u1ecdc ph\u00e2n t\u1eed, ch\u1ec9 m\u1ed9t sai s\u00f3t nh\u1ecf trong thao t\u00e1c c\u0169ng c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn k\u1ebft qu\u1ea3 d\u01b0\u01a1ng t\u00ednh gi\u1ea3, g\u00e2y \u1ea3nh h\u01b0\u1edfng nghi\u00eam tr\u1ecdng \u0111\u1ebfn \u0111\u1ed9 tin c\u1eady c\u1ee7a x\u00e9t nghi\u1ec7m. M\u1ed9t trong nh\u1eefng nguy\u00ean nh\u00e2n ph\u1ed5 bi\u1ebfn nh\u1ea5t l\u00e0 DNA\/RNA t\u1ea1p nhi\u1ec5m ph\u00e1t t\u00e1n t\u1eeb m\u1eabu ho\u1eb7c t\u1eeb kh\u00f4ng kh\u00ed trong ph\u00f2ng th\u00ed nghi\u1ec7m. \u0110i\u1ec1u n\u00e0y kh\u00f4ng ch\u1ec9 l\u00e0 v\u1ea5n \u0111\u1ec1 k\u1ef9 thu\u1eadt trong c\u00e1c quy tr\u00ecnh PCR hay Real-time PCR<\/a><\/strong>, m\u00e0 c\u00f2n l\u00e0 r\u1ee7i ro l\u1edbn trong s\u1ea3n xu\u1ea5t sinh ph\u1ea9m, n\u01a1i y\u00eau c\u1ea7u ki\u1ec3m so\u00e1t t\u1ea1p nhi\u1ec5m tuy\u1ec7t \u0111\u1ed1i. \u0110\u1ec3 \u0111\u1ea3m b\u1ea3o ch\u1ea5t l\u01b0\u1ee3ng x\u00e9t nghi\u1ec7m v\u00e0 nghi\u00ean c\u1ee9u, vi\u1ec7c ki\u1ec3m so\u00e1t t\u1ea1p nhi\u1ec5m c\u1ea7n \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n to\u00e0n di\u1ec7n kh\u00f4ng ch\u1ec9 b\u1eb1ng c\u00e1c dung d\u1ecbch kh\u1eed nhi\u1ec5m b\u1ec1 m\u1eb7t<\/strong>, m\u00e0 c\u00f2n b\u1eb1ng gi\u1ea3i ph\u00e1p l\u00e0m s\u1ea1ch kh\u00f4ng kh\u00ed trong ph\u00f2ng th\u00ed nghi\u1ec7m. Trong \u0111\u00f3, m\u00e0ng l\u1ecdc HEPA<\/a><\/strong> \u0111\u01b0\u1ee3c xem l\u00e0 c\u00f4ng ngh\u1ec7 c\u1ed1t l\u00f5i gi\u00fap lo\u1ea1i b\u1ecf hi\u1ec7u qu\u1ea3 aerosol ch\u1ee9a DNA\/RNA v\u00e0 vi sinh v\u1eadt, mang l\u1ea1i m\u00f4i tr\u01b0\u1eddng l\u00e0m vi\u1ec7c an to\u00e0n v\u00e0 \u201cDNA\/RNA-free\u201d.<\/p>\n\n\n\n

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1. Gi\u1ea3i ph\u00e1p hi\u1ec7n nay kh\u00f4ng ch\u1ec9 d\u1eebng \u1edf kh\u1eed nhi\u1ec5m b\u1ec1 m\u1eb7t<\/strong><\/h2>\n\n\n\n

\u0110\u1ec3 h\u1ea1n ch\u1ebf r\u1ee7i ro, nhi\u1ec1u ph\u00f2ng lab hi\u1ec7n nay \u0111ang s\u1eed d\u1ee5ng TopCLEAN\u00ae DNA\/RNA AWAY<\/strong> <\/a>– dung d\u1ecbch kh\u1eed nhi\u1ec5m chuy\u00ean d\u1ee5ng gi\u00fap lo\u1ea1i b\u1ecf nhanh v\u00e0 tri\u1ec7t \u0111\u1ec3 DNA\/RNA ngo\u1ea1i sinh tr\u00ean b\u1ec1 m\u1eb7t, d\u1ee5ng c\u1ee5 v\u00e0 thi\u1ebft b\u1ecb. Dung d\u1ecbch n\u00e0y an to\u00e0n, kh\u00f4ng \u0103n m\u00f2n, kh\u00f4ng t\u1ea1o h\u01a1i \u0111\u1ed9c, v\u00e0 r\u1ea5t hi\u1ec7u qu\u1ea3 cho vi\u1ec7c x\u1eed l\u00fd DNA\/RNA t\u1ea1p nhi\u1ec5m \u0111\u00e3 b\u00e1m tr\u00ean b\u1ec1 m\u1eb7t.<\/p>\n\n\n\n

Tuy nhi\u00ean, t\u00e1c nh\u00e2n g\u00e2y nhi\u1ec5m kh\u00f4ng ch\u1ec9 t\u1ed3n t\u1ea1i tr\u00ean b\u1ec1 m\u1eb7t, m\u00e0 c\u00f2n c\u00f3 th\u1ec3 l\u01a1 l\u1eedng trong kh\u00f4ng kh\u00ed d\u01b0\u1edbi d\u1ea1ng aerosol. V\u00ec v\u1eady, song song v\u1edbi vi\u1ec7c kh\u1eed nhi\u1ec5m b\u1ec1 m\u1eb7t, vi\u1ec7c duy tr\u00ec m\u00f4i tr\u01b0\u1eddng kh\u00f4ng kh\u00ed s\u1ea1ch c\u0169ng \u0111\u00f3ng vai tr\u00f2 then ch\u1ed1t. Gi\u1ea3i ph\u00e1p hi\u1ec7u qu\u1ea3 nh\u1ea5t hi\u1ec7n nay ch\u00ednh l\u00e0 m\u00e0ng l\u1ecdc HEPA<\/a><\/strong>, c\u00f4ng ngh\u1ec7 c\u00f3 kh\u1ea3 n\u0103ng lo\u1ea1i b\u1ecf aerosol ch\u1ee9a DNA\/RNA v\u00e0 vi sinh v\u1eadt.<\/p>\n\n\n\n

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2. Aerosol \u2013 Ngu\u1ed3n g\u00e2y nhi\u1ec5m ti\u1ec1m \u1ea9n trong ph\u00f2ng th\u00ed nghi\u1ec7m sinh h\u1ecdc ph\u00e2n t\u1eed<\/strong><\/h2>\n\n\n\n

Trong m\u00f4i tr\u01b0\u1eddng ph\u00f2ng th\u00ed nghi\u1ec7m, aerosol (hay c\u00f2n g\u1ecdi l\u00e0 sol kh\u00ed<\/em>) l\u00e0 t\u1eadp h\u1ee3p c\u00e1c h\u1ea1t r\u1eafn ho\u1eb7c gi\u1ecdt ch\u1ea5t l\u1ecfng c\u1ef1c nh\u1ecf l\u01a1 l\u1eedng trong kh\u00f4ng kh\u00ed. Ch\u00fang c\u00f3 th\u1ec3 t\u1ed3n t\u1ea1i t\u1eeb v\u00e0i gi\u00e2y \u0111\u1ebfn v\u00e0i ph\u00fat, g\u1ea7n nh\u01b0 v\u00f4 h\u00ecnh, nh\u01b0ng l\u1ea1i l\u00e0 ngu\u1ed3n l\u00e2y nhi\u1ec5m ch\u00e9o nguy hi\u1ec3m nh\u1ea5t trong c\u00e1c th\u00ed nghi\u1ec7m sinh h\u1ecdc ph\u00e2n t\u1eed. Aerosol c\u00f3 th\u1ec3 ph\u00e1t sinh t\u1eeb r\u1ea5t nhi\u1ec1u ngu\u1ed3n kh\u00e1c nhau tuy nhi\u00ean \u0111\u1ed1i v\u1edbi m\u1ed9t ph\u00f2ng th\u00ed nghi\u1ec7m sinh h\u1ecdc ph\u00e2n t\u1eed chuy\u00ean v\u1ec1 PCR v\u00e0 Real-time PCR th\u00ec nh\u1eefng thao t\u00e1c ho\u1eb7c thi\u1ebft b\u1ecb th\u01b0\u1eddng s\u1ebd t\u1ea1o ra aerosol bao g\u1ed3m:<\/p>\n\n\n\n